You are not watching CGI. Despite the kaleidoscope of colors and shapes rising from the infinite horizon, this is all real footage of the 12-mile Yurikamome line in Tokyo. Hold onto your butts.
     |
obama birth certificate nick cannon lindsay lohan saturday night live snl lindsay lohan valley fever project x the lorax
Some consolidation in the area of cloud services for enterprises: Intuit, the business services company that targets SMEs, is buying Elastic Intelligence, creators of Connection Cloud, a product that helps SMEs create DIY cloud-based apps. Financial terms of the deal were not disclosed.Source: http://feedproxy.google.com/~r/Techcrunch/~3/lirPygitVH8/
Demi Lovato iOS 6 Features big brother iOS 6 bank of america Yunel Escobar Eye Black Cruel Summer
Fujifilm's about to extend its line of mirrorless shooters packing manual dials and vintage looks, if a leak from Digicame Info is to be believed. The Japanese rumor site has flaunted pictures of a purported X-M1 model, which bears a strong resemblance to X-E1 we saw last year, minus the electronic viewfinder and shutter-speed selector dial. In place of the latter is a general mode selector, along with a tiltable LCD screen and WiFi, judging by the pictures above and after the break. While all that points to a cheaper model aimed at more casual shooters, there's no word from the company about specs, pricing or a release date, obviously. As soon as we hear, of course, you'll be the first to know.
Filed under: Cameras
Source: Digicame Info (translated)
Olympic Medal Count 2012 Olympics 2012 Olympic Schedule 2012 NBC Olympics NBC Olympics schedule 2012 Olympics Chad Everett
Russian Foreign Minister Sergey Lavrov speaks to the media after his meeting with Italian Foreign Minister Emma Bonino, unseen, in Moscow, Russia, Saturday, June 15, 2013. Russia's foreign minister says the evidence put forth by the United States of chemical weapons use in Syria apparently doesn't meet stringent criteria for reliability. (AP Photo/Alexander Zemlianichenko)
Russian Foreign Minister Sergey Lavrov speaks to the media after his meeting with Italian Foreign Minister Emma Bonino, unseen, in Moscow, Russia, Saturday, June 15, 2013. Russia's foreign minister says the evidence put forth by the United States of chemical weapons use in Syria apparently doesn't meet stringent criteria for reliability. (AP Photo/Alexander Zemlianichenko)
ST.PETERSBURG, Russia (AP) ? Russia's foreign minister has strongly warned that an international conference intended to negotiate peace for Syria could be derailed if the U.S. decides to push for a no-fly zone over the country.
Sergey Lavrov, speaking in an interview with The Associated Press and the Bloomberg news agency on Friday, also warned against pushing the demand for Syrian President Bashar Assad to step down, calling it unrealistic. He accused the West of sending conflicting signals to the Syrian opposition, encouraging rebels to keep fighting.
He said that supplies of weapons to the Syrian opposition promised by Washington and under consideration by the EU would be a "very big mistake."
A time and place for the international conference on Syria hasn't been announced yet.
Associated PressAdam Lanza Facebook the hobbit mick jagger Newton Shooting Newtown Shooting Gangnam Style Ryan Lanza
This is gonna be a classy Friday night. You don't have to groove to Duke Ellington all the time, but when you do you should turn on Jack The Bear. This chart showcases Jimmy Blanton (Jack the bear...get it?), a bassist who at 22 brought the band to a new level in the early 1940s. Even if you hate 32-bar form and blues choruses, or you think pretentious nonsense is happening right now, listen to the end of the track for the bass solo. That's what it sounds like when someone nails it. [Amazon, iTunes, Spotify]
Source: http://gizmodo.com/duke-ellington-jack-the-bear-536409718
Grammy nominations 2013 Lynsi Torres Fall Out Boy Alabama hostage mta Beyonce Superbowl nemo
Mobile devices can be an asset to any modern organization. As more companies adopt bring-your-own-device (BYOD) policies, deploying these programs is becoming essential in order to remain competitive. Businesses with increased mobility enjoy benefits such as cost savings, increased productivity, higher employee engagement and more, so it's critical that firms aren't left behind if they want to rise to the top of their respective industries.
However, there are some risks that come with engaging in BYOD, including threats to data protection. Dark Reading reported that according to a Check Point report, 79 percent of enterprises have experienced a mobile-related security issue in the past year. The study found that among the 67 percent of organizations that acknowledged that they allow personal gadgets to access their networks, 88 percent of smartphones and tablets were used for email, 53 percent were storing client information and 49 percent contained corporate data within business apps. Nearly half (48 percent) additionally had network logins saved.
However, despite these usage patterns, Check Point revealed that many businesses are not taking the necessary action to prevent risk factors from causing data breaches. In fact, 63 percent of respondents said that their company does not make an effort to manage enterprise-related information on employee-owned endpoints.
In order to maximize security, 1to1Media?pointed out that businesses should?take proactive steps to manage device use. The source noted that an Ovum study advised that businesses learn?about why workers engage in BYOD and what behaviors they engage in while on mobile devices, as well as gain insight into their staff's opinions on data security, including application use. Knowing how employees approach BYOD may help leaders develop more comprehensive policies and implement more effective solutions for data loss prevention.
iCarly banana republic gap Victoria Secret Bath And Body Works Dicks Sporting Good office max
Source: http://moviesblog.mtv.com/2013/06/21/world-war-z-review-flatbush-zombies/
Ada Lovelace 12/12/12 manny pacquiao Chopper Live jerry brown michael buble michael buble
June 20, 2013 ? A line of genetically modified mice that Western University scientists call "Forrest Gump" because, like the movie character, they can run far but they aren't smart, is furthering the understanding of a key neurotransmitter called acetylcholine (ACh). Marco Prado, PhD, and his team at Robarts Research Institute say the mice show what happens when too much of this neurotransmitter becomes available in the brain. Boosting ACh is a therapeutic target for Alzheimer's disease because it's found in reduced amounts when there's cognitive failure.
Prado's research is published in the Journal of Neuroscience.
"We wanted to know what happens if you have more of the gene which controls how much acetylcholine is secreted by neurons," says Prado, a Robarts scientist and professor in the Departments of Physiology and Pharmacology and Anatomy and Cell Biology at Western's Schulich School of Medicine & Dentistry. "The response was the complete opposite of what we expected. It's not a good thing. Acetylcholine release was increased threefold in these mice, which seemed to disturb cognitive function. But put them on a treadmill and they can run twice as far as normal mice before tiring. They're super-athletes." In addition to its function in modulating cognitive abilities, ACh drives muscle contraction which allowed for the marked improvement in motor endurance.
One of the tests the scientists, including first author Benjamin Kolisnyk, used is called the touch screen test for mice (video is available showing the test) which uses technology similar to a tablet. After initiating the test, the mice have to scan five different spots on the touch screen to see a light flash, and then run and touch that area. If they get it right they get a reward. Compared to the control mice, the "Forrest Gump" mice failed miserably at the task. The researchers found the mice, which have the scientific name ChAT-ChR2-EYFP, had terrible attention spans, as well as dysfunction in working memory and spatial memory.
Prado interprets the research as showing ACh is very important for differentiating cues. So if your brain is presented with a lot of simultaneous information, it helps to pick what's important. But when you flood the brain with ACh, your brain loses the ability to discern what's relevant. This study was funded mainly by the Canadian Institutes of Health Research.
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by University of Western Ontario.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Note: If no author is given, the source is cited instead.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/WcpxTniHGD8/130620111232.htm
sacha baron cohen ryan seacrest octavia spencer meryl streep oscars school shooting ohio billy crystal oscar winners 2012 billy crystal oscars 2012
It's often been rumored that Microsoft had an eye on Nokia's handset business. It made perfect sense for both companies -- one a struggling pioneer of the mobile industry and the other a struggling stalwart from the first wave of smartphones. According to the Wall Street Journal's sources, the two were actually quite close to striking a deal and were having "advanced talks" in London as recently as this month. But, according to the all-too-familiar "people familiar with the matter," those talks have broken down. Those same sources say it was Microsoft that walked away from the table over concerns about Nokia's asking price, especially in light of its continued failure to put a significant dent in Apple and Samsung's market share. Though it seems like dreams of a Microsoft-Nokia merger are dead for the moment, don't expect the disagreement to severely affect the duo's partnership. Nokia is still reliant on Microsoft's help to stand out in the market and Microsoft needs the Finnish manufacturer to keep pumping out flagship handsets with Windows Phone on them.
Filed under: Cellphones, Mobile, Microsoft, Nokia
Source: Wall Street Journal
Miss Universe 2012 x factor x factor john kerry eastbay Samantha Steele Dec 21 2012
The president, it seems, committed a minor gaffe during this week's G-8 meetings in Northern Ireland. According to the Financial Times, the stumble came during a discussion of tax avoidance issues, when Barack Obama thrice interrupted the British chancellor of the exchequer in order to say he agreed with "Jeffrey."
The chancellor's name is George Osborne.
Obama later apologized, saying, "I'm sorry, man. I must have confused you with my favorite R&B singer." The U.S. leader was referring to Jeffrey Osborne, the soulful crooner responsible for "On the Wings of Love."
But is Osborne really the favorite that Obama claims? Some investigative reporting has raised serious questions about where Osborne ranks in Obama's hierarchy of musical preferences.
In multiple interviews about music, Obama has never once mentioned Osborne when asked about the songs he listens to, even when mentioning other R&B artists. Consider the following data points:
So -- is Jeffrey Osborne really an artist so close to the president's heart that he could accidentally blurt out his name when addressing another country's chancellor of the exchequer? Or did Obama just forget poor George Osborne's name?
We report, you decide.
marlins facebook buys instagram kevin systrom fibonacci sequence maryland lottery grand jury ozzie guillen fidel castro
WASHINGTON (AP) ? Michael Froman, a senior White House economic adviser and classmate of President Barack Obama at Harvard Law School, on Wednesday won Senate confirmation to be the next U.S. trade representative.
The confirmation vote was 93-4, elevating the 50-year-old Froman to the head of an agency now involved in two of the most significant trade deals in recent history.
"In his new position, Mike will stay focused on our primary economic goals - promoting growth, creating jobs and strengthening the middle class," Obama said in a statement lauding the Senate's action. "And he will continue to help open new markets for American businesses, level the playing field for American workers, farmers and ranchers, and fully enforce our trade rights."
Voting against From were an independent, Bernie Sanders of Vermont, and three Democrats: Carl Levin of Michigan, Joe Manchin of West Virginia and Elizabeth Warren of Massachusetts. Warren said in a floor speech that she was voting against the nominee because he would not commit to more transparency on positions taken by the United States and other countries in trade negotiations.
"I believe we need a new direction from the trade representative, a direction that prioritizes transparency and public debate," she said.
Froman, nominated by Obama in May, succeeds former Dallas Mayor Ron Kirk, who resigned as USTR in February after serving through Obama's first term and finalizing free trade agreements with South Korea, Panama and Colombia.
Froman has been serving as deputy national security adviser for international economic affairs and has been involved in coordinating White House policy on international trade, investments and energy.
When he announced Froman's nomination, Obama credited him with helping negotiate the three free trade agreements.
One of his main responsibilities as USTR will be meeting a goal to complete negotiations this year on the Trans-Pacific Partnership, an Asian-Pacific trading bloc that includes the U.S., Australia, Canada, Malaysia, Mexico, Vietnam, Chile, New Zealand, Brunei, Singapore, Peru and Japan.
The trade office will also be at the forefront of just-initiated trade liberalization talks with the European Union known as the Transatlantic Trade and Investment Partnership.
"He's very smart, he's very tough, he's the right person for the job as the United States begins to negotiate trade agreements with Asia, the so-called TPP, as well as trade agreements with the Europeans," said Senate Finance Committee Chairman Max Baucus, D-Mont., in support of the nominee.
Froman worked as Treasury Secretary Robert E. Rubin's chief of staff during the Bill Clinton administration, He was a managing partner at Citigroup and a senior fellow at the Council on Foreign Relations before joining the Obama administration.
Source: http://news.yahoo.com/senate-backs-froman-next-trade-representative-223706049.html
Kordell Stewart cesar chavez Wichita State hbo Buckwild Steve Alford Phil Spector
WASHINGTON (AP) ? After secretive talks, key senators expressed optimism Wednesday night that they were closing in on a bipartisan agreement to toughen the border security requirements in immigration legislation that also offers a path to citizenship to millions living in the country illegally.
Under the emerging compromise, the government would grant legal status to immigrants living in the United States unlawfully at the same time the additional security was being put into place. Green cards, which signify permanent residency status, would be withheld until the security steps were complete.
If agreed to, the change has the potential to give a powerful boost to the immigration bill that is at the top of President Barack Obama's second-term domestic agenda.
The developments came as Democrats who met with House Speaker John Boehner during the day quoted him as saying he expects the House to pass its own version of an immigration bill this summer and for Congress to have a final compromise by year's end. Boehner, R-Ohio, has already said the legislation that goes to the House in the next month or two will not include a pathway to citizenship for those in the United States illegally.
Precise details of the pending agreement in the Senate were unavailable, although the legislation already envisions more border agents; additional fencing along the U.S-Mexico border; surveillance drones; a requirement for employers to verify the legal status of potential workers; as well as a biometric system to track foreigners who enter and leave the United States at air and seaports and by land.
"Our whole effort has been to build a bipartisan group that will support the bill," said Sen. John Hoeven, R-N.D., who has not yet stated a position on the legislation. "That's what this is all about, and it's focused on border security."
Sen. Chuck Schumer, D-N.Y., one of the bill's most prominent supporters, said discussions with Republicans "have been really productive. We've made a lot of progress in the last 24 hours. Now we have some vetting to do with our respective allies."
The potential compromise came into focus one day after the Congressional Budget Office jolted lawmakers with an estimate saying that as drafted, the legislation would fail to prevent a steady increase in the future in the number of residents living in the United States illegally.
The estimate appeared to give added credibility to Republicans who have been pressing Democrats to toughen the border security provisions already written into the bill. Schumer and Sen. Bob Menendez, D-N.J., met at midday with Hoeven, and Republican Sens. Bob Corker of Tennessee, John McCain of Arizona and Lindsey Graham of South Carolina. The Democrats, McCain and Graham are part of the so-called bipartisan Gang of Eight that drafted the bill.
If ratified, the compromise would mark concessions on both sides.
Some Republicans have been unwilling to support a bill that grants legal status to immigrants in the country illegally until the government certifies that the border security steps have achieved 90 percent effectiveness.
On the other hand, Democrats have opposed Republican proposals to make legalization contingent on success in closing the border to illegal crossings. Under the legislation as drafted, legalization could begin as soon as a security plan was drafted, but a 10-year wait is required for a green card.
One plan to change that was sidetracked during the day on a vote of 61-37.
Sen. Rand Paul, R-Ky., said his proposal would require Congress to vote annually for five years on whether the border is secure. If lawmakers decide it is not, "then the processing of undocumented workers stops until" it is, he said. The decision would be made based on numerous factors, including progress toward completion of a double-layered fence along the U.S.-Mexico border and toward a goal of 95 percent capture of illegal entrants. A system to track the border comings and goings of foreigners is also required.
Only a day earlier, the CBO had cheered supporters of the bill with an estimate that it would help the economy and reduce deficits in each of the next two decades.
Now it was the skeptics' turn to crow.
"Illegality will not be stopped, but it will only be reduced by 25 percent," said Sen. Jeff Sessions, R-Ala., referring to the prediction by the non-partisan CBO.
While the public debate was taking place, lawmakers involved in the private talks expressed optimism.
"We're on the verge of doing something dramatic on the border," Graham told reporters. "What we're trying to do is put in place measures that to any reasonable person would be an overwhelming effort to secure our border. This is a key moment in the effort to pass the bill."
Across the Capitol, House Republican leaders sought to present a friendlier face to Hispanics ? a group that gave Obama more than 70 percent support in last year's presidential election.
Boehner met with the Democratic-dominated Congressional Hispanic Caucus, while rank and file members of his party reviewed areas of agreement with faith-based Latino leaders.
"It's a conversation Republicans want to have," Rep. Cathy McMorris Rodgers, R-Wash., said later at a news conference outside the Capitol.
At the same time, though, anti-immigration protesters moved across the Capitol plaza into range of television cameras, raising signs that said, "Do Not Reward Criminals" and "No Amnesty for Illegal Aliens."
Separately, the House Judiciary Committee worked on legislation creating a program allowing farm workers to come to the United States to take temporary jobs in the United States.
The measure is one of several that the panel is considering in the final weeks of June as part of a piece-by-piece approach to immigration rather than the all-in-one bill that Senate is considering.
In addition to border security measures and a pathway to citizenship for millions of immigrants in the country illegally, the Senate bill provides more visas for highly-skilled workers prized by the technology industry, a guest worker farm program and a new program for lower-skilled workers to come to the United States.
___
Associated Press writer Laurie Kellman contributed to this report.
Source: http://news.yahoo.com/compromise-among-senators-eyed-border-security-225125834.html
Colin Kaepernick Chris Culliver Atlanta school shooting Superbowl Kickoff Time 2013 30 rock What Time Is The Super Bowl 2013 Super Bowl 2013 Time
Chinese fund managers are giving local investors a chance to cash in on the U.S.?s recovering property market without any of the regulatory headaches that come with trying to buy a home abroad.
Guangzhou-based GF Fund Management Co. is launching two funds?one denominated in dollars, the other in yuan?that will buy shares in the 120 real-estate investment trusts tracked by the MSCI U.S. REIT Index, which is seen as a proxy for the U.S. real-estate market.
The funds will be launched on July 8 and offered to retail and institutional investors at banks and brokerages. The minimum investment is 1,000 yuan ($163), which could draw middle-class investors.
?We?ve had requests from investors here to launch a U.S. real estate-related product,? said GF Chairman Wang Zhiwei. ?People comparing property prices in the U.S. and China said the lower prices in the U.S.?and the potential for higher returns?make it more attractive.?
More affluent investors are also looking to diversify their assets, and they feel that investing in the U.S. makes sense given the recovering economy there, said David Qiu, GF?s global investment portfolio manager.
Chinese nationals looking to buy a home abroad face numerous barriers, such as having to find ways to get around the $50,000 annual cap on overseas investments.
Mr. Wang said such restrictions make GF?s soon-to-be launched funds a more viable alternative. China has no locally listed REITs.
GF will be making its investments through China?s Qualified Domestic Institutional Investor program, through which Chinese institutional investors are able to invest in overseas securities within predetermined quotas.
Mr. Qiu said that GF had received a $1 billion QDII quota in 2009, and has only used around $200 million so far.
He declined to say how much GF is hoping to raise for these funds, but added the funds are unlikely to have any impact on the U.S. property market.
Word of GF?s funds comes after Guotai Asset Management Co. said last week it had launched an equity fund tracking U.S. companies in the real-estate supply chain, noting that the recovery in the local property sector appears more solid than it was a year earlier.
Other fund managers have more long-standing funds focused on the U.S. Penghua Fund Management?s U.S. property fund, which also invests in REITS, has had an investment yield of 10.6% since its launch in 2011, according to its website.
But such returns aren?t guaranteed. Property stocks in the U.S. had a turbulent run during the subprime crisis in 2008 and were slugging during the ensuing downturn. The MSCI U.S. REIT Index recorded a 13.1% return in the past year?but its five-year return was? just 3%.
The stocks in the MSCI U.S. REITS Index have a combined market capitalization of $507 billion.
? Esther Fung
Like China Real Time on Facebook and follow us Twitter for the latest updates.
Kerri Strug Ledecky Nadia Comaneci Rebecca Soni Snoop Lion London 2012 Table Tennis badminton
All Critics (55) | Top Critics (15) | Fresh (51) | Rotten (3)
The Brothers Grimm would have been surprised, possibly amused.
A sensual and sophisticated retelling of a beloved fairytale re-imagined as a homage to European silent cinema, Spanish writer-director Pablo Berger's black-and-white Blancanieves will leave you transfixed.
Most films are experiences to be ignored or at best forgotten. "Blancanieves" is a little classic to be treasured.
It is a full-bodied silent film of the sort that might have been made by the greatest directors of the 1920s, if such details as the kinky sadomasochism of this film's evil stepmother could have been slipped past the censors.
Blancanieves, which won 10 Goyas (Spain's equivalent of the Oscars) and was a smash hit in its native Spain, has traces of a kinky undertone and an uncommon willingness to embrace the darkness inherent in this fairy tale.
As if bewitched, the legend of Snow White is transferred to Seville in the early twentieth century and transformed into high melodrama.
Blancanieves is painstakingly crafted, emotionally gripping at times, and more authentically Grimm than most interpretations, and it puts a slightly unsettling new spin on Prince Charming and the proverbial happily-ever-after ending.
The film is -- to understate the matter -- overconceptualized.
Like The Artist, Blancanieves is delightfully novel, but it also feels trapped by its innovative gimmickry.
A boldly conceived fairy tale from Spain
Succeeds in all its cinematic experiments
The story might be familiar, but Berger's film is so beautifully shot and so wonderfully scored - and so distinctively Spanish - that it stands as its own film.
Blancanieves holds to the structure, but not strictures, of the source fairy tale.
A new, purely silent movie from Spain that never once speaks and doesn't need to speak. What's more, it seems to get the infinite possibilities of silence, and how much passion can come from it.
Berger's film doesn't show loyalty to any traditional version of Snow White. Berger's Blancanieves takes a darker approach, which seems appropriate.
A completely enchanting fairy tale about the vicissitudes of fate, in live action and glorious black and white.
The fun in the Spanish "Blancanieves" is the way it plays with our expectations.
May not have much depth to its characters or particular surprise, but its lovely depiction of family's ability to harm and mend has the flair of flamenco and the sorrow of opera.
No, "Blancanieves" isn't subtle, but it's an unforgettable time at the movies.
Inspired filmmaking steeped in the imagery of silent film history, a dark Iberian strain of Roman Catholicism and the magic of fairy tales.
... lusty and heartfelt, fiery flamenco and spirited country jig. Don't go expecting a Disney-fied fable. Berger seasons with S&M and the kind of macabre touches you'd expect in vintage Browning or Bunuel.
If not for some faintly disturbing imagery and a pleasingly feminist heroine, you could mistake this for a movie actually made in the 1920s (and even those two factors weren't utterly unknown then).
No quotes approved yet for Blancanieves. Logged in users can submit quotes.
Source: http://www.rottentomatoes.com/m/blancanieves/
world war z groundhog day Ed Koch Groundhog Day 2013 What Time Is The Superbowl Caleb Moore House of Cards
AP
Posted on June 19, 2013 at 9:14 PM
Updated yesterday at 9:17 PM
OMAHA, Neb. (AP) -- Matt Boyd pitched a four-hitter and struck out 11 and Oregon State made a fourth-inning sacrifice fly stand for a 1-0 victory over Indiana in the College World Series on Wednesday night.
The Beavers (52-12) won the first 1-0 game at the CWS since 1985. They now face Mississippi State on Friday needing to beat the Bulldogs twice to reach next week's finals.
The Hoosiers (49-16) went 1-2 in their first CWS appearance and were shut out for the first time this season.
Indiana's Aaron Slegers allowed seven hits in his first career complete game.
Boyd, who pitched his fourth complete game and third shutout this season, flummoxed the Hoosiers with his mix of fastballs and off-speed pitches. He faced the minimum through four innings. The senior left-hander held the Hoosiers hitless until Michael Basil looped a ball into short right field in the fifth. Basil moved to second on Dustin DeMuth's bunt single, but no Hoosiers runner advanced farther.
The Beavers scored in the fourth when Kavin Keyes singled, went to third on Ryan Barnes' double and came home on Jake Rodriguez's sacrifice fly to right.
Boyd earned his first win in five starts since May 10 against Stanford. He had a loss and three no-decisions in between.
The Beavers played error-free defense behind Boyd, picked off runners in the first and third innings and turned a double play in the sixth. Boyd, who was drafted in the sixth round by Toronto, took the loss in that game, allowing a run on two hits in an inning of relief of Andrew Moore.
Big Ten champion Indiana was the first team from the conference to make it to the CWS since Michigan in 1984. The Hoosiers were the first from the Big Ten to win a game here since the Wolverines beat Stanford in 1983. But they struggled offensively, particularly against left-handed pitching, after batting .309, averaging 9.4 runs and hitting six home runs in their first five tournament games. The Hoosiers batted .211 and scored a total of six runs in three CWS games.
Source: http://www.kgw.com/sports/Oregon-State-stays-alive-in-College-World-Series-212258981.html
Olympics Opening Ceremony Katherine Jackson Olympics Opening Ceremony Time US weekly Sally Ride Ichiro minka kelly
A new film claims the official government report on the crash of TWA Flight 800 in 1996 is an elaborate?fabrication, but the most shocking part of the story is that charges are being leveled by some of the very investigators who put the report together. Six experts who appear in the film were members of the?National Transportation Safety Board investigation team that concluded the crash was an accident, but they now claim they were silenced by their superiors. The movies, "TWA Flight 800" will debut on EPIX TV next month, on the 17-year anniversary of the crash.
TWA Flight 800 was en route from JFK Airport in New York to Paris, France, when it exploded and crashed off the coast of Long Island, killing all 230 people on board. From the very beginning, there were some who?speculated?that the plane was the victim of a terrorist attack, leading the FBI to conduct its own criminal investigation. Among the?possibilities?that were suggested as the cause were a bomb in the cargo hold, or an anti-aircraft missile. Several witnesses even claimed they saw an object or streak of light that looked liked a missile or rocket moving toward the plane before it exploded.
The final NTSB reported said that faulty wiring connected to a central fuel tank caused a blast that destroyed the fuesalage, however, there were still many skeptics and conspiracy theorists who have long doubted that official story. In one particularly famous example, Pierre Salinger, a former Press Secretary for President John Kennedy and reporter for ABC News, claimed?he'd seen proof that the U.S. Navy shot down the plane and then covered it up.
Now, those theories are likely to get a new airing, thanks to accident investigators who worked on the TWA 800 case, but say they were not allowed to speak up at the time of the official report. The experts include NTSB and TWA accident investigators, who say they are only able to speak up now that they are retired. According their statements in the film, they believe the official explanation is wrong and the damage was caused by an explosion that came from outside the plane.
The filmmakers won't speculate on what could have caused such an explosion, and haven't yet offered up evidence to support their theory (you'll have to watch on July 17), but they are asking the NTSB to re-open the investigation. Whether or not that happens, or even if a follow-up reaches the same conclusions as the original, this new film will ensure that the alternate theories and claims up a cover will probably never be put to rest.
Source: http://news.yahoo.com/twa-flight-800-investigators-claim-official-crash-story-120157562.html
Little Nemo gawker Romney Bosses Day 2012 Arlen Specter Winsor McCay Amanda Todd
June 19, 2013 ? Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy -- "intrinsically disordered." In this week's issue of Nature, scientists at The Scripps Research Institute (TSRI) report their discovery of an important trick that a well-known intrinsically disordered protein (IDP) uses to expand and control its functionality.
"We've found what is probably a general mechanism by which IDPs modulate their activities," said TSRI Professor Peter E. Wright, who is Cecil H. and Ida M. Green Investigator in Biomedical Research and member of TSRI's Skaggs Institute for Chemical Biology. Wright was a senior investigator for the study, along with TSRI Associate Professor Ashok A. Deniz.
The study focused on an IDP known as the adenovirus "early region 1A oncoprotein" (E1A). An adenovirus starts producing copies of E1A shortly after it infects a cell. E1A proteins interact with a variety of key cellular molecules to quickly subvert the cell's replication machinery for the benefit of the virus.
Links to Disease
E1A is worth studying not just because it facilitates adenovirus infections, but also because it's a prime example of an IDP. Such proteins frequently play outsized roles in cells, as crucial "molecular hubs" within very large protein-interaction networks. IDPs also include proteins that are linked to major diseases, including the tumor suppressor protein p53, the alpha synuclein protein of Parkinson's disease, and the amyloid beta and tau proteins of Alzheimer's disease.
The simple, flexible structures of IDPs are often promiscuously "sticky," which in principle explains why they would have multiple molecular partners. But IDPs don't connect willy-nilly with other proteins, and scientists have wondered how they regulate their diverse interactions.
Wright's laboratory and others have been studying these interactions using a technique called nuclear magnetic resonance (NMR) spectroscopy. However, E1A's intrinsic stickiness means that it tends to aggregate at NMR-friendly concentrations, rendering this method of analysis problematic. (Most proteins, by folding up into complex shapes, effectively cloak their stickier bits.)
A Sensitive Technique
For the new study, Wright and his colleagues turned to Deniz, whose laboratory specializes in the use of sensitive, cutting-edge techniques to study the dynamics of disordered proteins and other biological molecules. One of these techniques, a quantum optics method known as single-molecule FRET, uses a tiny fluorescent beacon system to register distances between selected parts of a protein. In effect, this allows investigators to monitor in real time the shape-changes of E1A -- characterized by Wright's laboratory in earlier work -- which mark its rapid couplings and uncouplings with other proteins.
"The technique is sensitive enough that we can use it at extremely low protein concentrations, even focusing on single E1A proteins to avoid the loss of information that comes from the usual averaging of results over multiple proteins," Deniz said.
Postdoctoral fellows Allan Chris M. Ferreon and Josephine C. Ferreon, in the Deniz and Wright laboratories, respectively, used the single-molecule FRET method to detail the strengths ("affinities") with which E1A binds to two of its most important protein partners. By mapping how these binding affinities change under different conditions, they were able to obtain key insights into how E1A manages its multiple interactions.
Achieving Complexity
First, like many folded proteins, E1A turns out to employ a basic regulatory mechanism called allostery: when one protein partner binds at one part of the E1A structure, it changes the ability of the other major binding site on E1A to bind other partners.
For most proteins that use allostery, this change makes partner-binding at the other site more likely ("positive cooperativity"). For a minority, it makes partner-binding at the other site less likely ("negative cooperativity"). But E1A turns out to have the capacity foreither positive cooperativity or negative cooperativity between its two major binding regions -- depending on whether a third part of the protein is occupied. "Allostery itself is a mechanism for modulating a protein's functions, and here we show that E1A takes it to another level by modulating allostery -- modulating the modulation, in effect," said Josephine Ferreon.
The finding helps explain how E1A generates and manages its functional complexity -- a complexity that for viral proteins seems particularly necessary, considering how tiny viral genomes are in comparison to those of their animal hosts. Moreover, some of E1A's key binding partners in infected cells are themselves hub-type IDPs. "So now you multiply the complexity -- and you can see how proteins such as E1A manage to achieve so much so quickly within a cell," said Allan Ferreon.
Wright regards the study as the start of a rewarding line of investigation using sensitive techniques such as single-molecule FRET. "The fact that we can get around the usual technical obstacles relating to IDPs and do these single-molecule experiments really opens up the study of IDP hub interactions," he said.
Deniz concludes, "We're definitely going to be studying more of these hub proteins, and I think we're going to discover other fundamental principles by which they achieve complex layers of biological regulation and function."
The study, "Modulation of allostery by protein intrinsic disorder" was funded by the National Institutes of Health (grants GM066833 and CA96865) and by the Skaggs Institute for Chemical Biology at TSRI.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/RNS8mzGQMhA/130619132442.htm
Mayweather Fight Mayweather Robert Guerrero may day 747 crash Kentucky Derby 2013 Barcelona
ISTANBUL (AP) -- Turkey's Islamic-led government is facing its biggest protests in years as demonstrators and police clashed Tuesday for the 12th straight day. Here's a look behind the scenes:
Q: What's going on in Turkey?
A: Demonstrators were camping out in a park in Istanbul's landmark Taksim Square, protesting plans to cut down trees and redevelop the area when police went in May 31 to clear them out. That heavy-handed raid ignited protests that have since spread to dozens of Turkish cities. On Tuesday, police went into the square again, pulling down protesters' makeshift barricades and chasing some with tear gas and water cannons.
Q: Is this just about trees ? or something else?
A: Protesters are venting pent-up resentment against Prime Minister Recep Tayyip Erdogan, who has been in office for 10 years. Many secular Turks see him as an authoritarian figure trying to force his conservative religious Islamic views on them. Erdogan rejects those accusations. Still, he has spoken out against Caesarean births, said women should have at least three children, and backed laws to curb the sale of alcohol.
Q: What does Erdogan say?
A: The prime minister says the protests are being instigated by extremists who want to blacken Turkey's international image and he has lost patience with them. "For those who want to continue with the incidents I say: 'It's over,'" Erdogan said Tuesday. "Not only will we end the actions, we will be at the necks of the provocateurs and terrorists, and no one will get away with it."
Q: Why should other nations care about Turkey?
A: Turkey, a largely Muslim nation that straddles Europe and Asia, is a stable democracy, a key U.S. ally and an important regional influence. It has taken in tens of thousands of Syrian refugees fleeing that country's civil war.
Turkey's economy is worth $1.3 trillion annually, almost as much as Canada's. It also has a flourishing tourist industry that welcomed nearly 38 million visitors last year to ancient historical sites and ruins, wide sandy Mediterranean beaches and stunning regions of natural beauty.
Q: How is Turkey a key U.S. ally?
A: Turkey borders Iran, Iraq and Syria. The U.S. needs Turkey's help to quell the violence in Syria, stabilize Iraq and stem Iran's nuclear ambitions. Turkey also played a key role as the U.S. military went after Iraqi dictator Saddam Hussein. Erdogan visited the White House last month for talks with President Barack Obama.
Q: What's next? Will Turkey see an Arab Spring revolution?
A: Turkey holds a presidential election next year in which Erdogan ? who will hit his term limit as prime minister ? could run against the current president. Despite the protests, Erdogan is unlikely to fall. His backing by rural conservative voters ? the so-called silent majority ? still appears to be strong.
Source: http://news.yahoo.com/look-turkey-widespread-protests-124622635.html
Suspects in Boston Bombing Kerry Rhodes Daft Punk Get Lucky Texas explosion Paul Kevin Curtis man of steel man of steel
June 13, 2013 ? As anyone who's ever mixed up the sugar and salt while baking knows, too much of a good thing can be inedible. What hasn't been clear, though, is how our tongues and brains can tell when the saltiness of our food has crossed the line from yummy to yucky -- or, worse, something dangerous.
Now researchers at the Johns Hopkins University School of Medicine and the University of California, Santa Barbara report that in fruit flies, at least, that process is controlled by competing input from two different types of taste-sensing cells: one that attracts flies to salty foods, and one that repels them. Results of their research are described in the June 14 issue of Science.
"The body needs sodium for crucial tasks like putting our muscles into action and letting brain cells communicate with each other, but too much sodium will cause heart problems and other health concerns," explains Yali Zhang, Ph.D., who led the recent study as part of his graduate work at Johns Hopkins. To maintain health, Zhang says, humans and other animals perceive foods with relatively low salt concentrations as tasty, but avoid eating things with very high salt content.
To find out how the body pulls off this balancing act, Zhang worked with his adviser, Craig Montell, Ph.D., a leading scientist in the field of sensory biology and now a professor at UC Santa Barbara, and graduate student Jinfei Ni to get an up-close view of the fly equivalent of a tongue: its long, curly proboscis. They zoomed in on the proboscis' so-called sensilla, hair-like structures that serve as the fly's taste buds.
Previous research had identified several distinct types of sensilla, one of which attracts flies to a taste, while another repels them. Zhang loaded an electrode with a mixture of water and different concentrations of salt, and touched it to each type of sensilla, using the same electrode to detect the electrical signals fired by the sensilla in response to the salt. He found that up to a point, increasing salt concentrations would produce increasingly strong electrical signals in the attractive sensilla, but after that point, the electrical signals dropped off as the concentration continued to rise. In contrast, the repellant sensilla gave off stronger and stronger electrical signals as the salt concentration rose.
Zhang said the team realized that the taste receptor cells in the attractive and repellant sensilla were likely locked in a tug-of-war over whether the fly would continue eating or go off in search of better food. At lower concentrations, the attractive signal would dominate the repellant signal, sending a cumulative message of "yum!" But at high concentrations, the repellant signal would overwhelm the attractive signal, sending the signal "yuck!"
To further test this conclusion, the team mutated a gene called Ir76b that codes for a protein they suspected was involved in the action of the attractive sensilla. To their great surprise, Zhang found that loss of Ir76b function caused flies to avoid the otherwise attractive low-salt food. The reason for this, he found, was that mutating Ir76b only impaired the responses of the attractive sensilla, leaving the repellant sensilla to win the day. Looking further into the action of the protein produced by Ir76b, the team found that it is a channel with a pore that lets sodium pass into the taste cells of the sensilla. Unlike most pores of this type, which have gates that must be opened by certain key chemical or voltage changes in their environment, this gate is always open, meaning that at any time, sodium can flood into the cell and spark an electrical signal. "It's an unusual setup, but it makes sense because the local sodium concentration outside taste receptor cells appears to be a lot lower than that surrounding most cells. The taste receptor cells don't need to keep the gate closed to protect themselves from that excess sodium," Zhang says.
Long before we humans started worrying about regulating our sodium intake, it was a problem all animals had to deal with, Zhang says, and thus his research has implications for other animals, including humans. Although animal taste buds and insect sensilla have different makeups, he suspects that the tug-of-war principle may apply to salt-tasting throughout the animal kingdom, given that different species behave similarly when it comes to salty foods. Identifying the low-salt sensor in humans could be particularly useful, he says, as it could lead to the development of better salt substitutes to help people control their sodium intake.
This study was funded by the National Institute on Deafness and Other Communication Disorders (DC007864).
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/TwMpfKhNB4A/130613142634.htm
jadeveon clowney orange bowl Rose Parade 2013 rex ryan Louisville football Fidelity Charlie Strong
VigLink is announcing an update to its VigLink Convert product that should help affiliate links stay up-to-date. The company promises to make publishers more money through affiliate links,?i.e. links to online merchants that can earn a commission if they lead to a purchase. With Convert, VigLink turns standard, existing links into affiliate links. (And it works with 30,000 online retailers.)Source: http://feedproxy.google.com/~r/Techcrunch/~3/VHdZ4Hy6qCw/
barack obama dear abby WRAL John Harbaugh jill biden jill biden martin luther king jr
COLORADO SPRINGS, Colo. (AP) ? Residents of 1,000 homes in Colorado Springs are being ordered to evacuate because of a wildfire that's already destroyed at least 360 houses.
Thursday's evacuation order is the first within the city limits. About 38,000 people already have been evacuated because of the fire that started in a populated, wooded area east of the city.
The city of about 430,000 people is also asking residents of 2,000 more homes to be ready to evacuate because the fire has reached a designated trigger point.
The blaze in the Black Forest area is now the most destructive in Colorado history.
THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP's earlier story is below.
A wildfire in a dry, densely wooded area of Colorado has destroyed at least 360 homes ? nearly four times the previous estimate and a number that seemed likely to climb as the flames kept burning out of control, authorities said Thursday.
The tally of lost homes was a dramatic increase from Wednesday evening, when 92 homes were listed as gone. The blaze in the Black Forest area northeast of Colorado Springs is now the most destructive in Colorado history, surpassing last year's Waldo Canyon fire, which burned 347 homes, killed two people and led to $353 million in insurance claims.
"I never in my wildest dreams imagined we'd be dealing a year later with very similar circumstances," said El Paso County Sheriff Terry Maketa. "Maybe we just had 20 to 30 years of luck."
Deputies still have not been able to verify the condition of 79 other homes, so the losses could rise.
Some of the homes that were previously listed as standing were destroyed as high winds pushed the 23-square-mile wildfire back into areas that had already burned, the sheriff said.
The number also rose because deputies worked through the night to assess the damage, although they were also pushed out by the flames at times.
"Houses we knew were standing yesterday I personally witnessed they were lost last night," Maketa said.
Fueled by hot temperatures, wind gusts and bone-dry forest conditions, the flames have also forced more evacuations. About 38,000 people who live in an area spanning nearly 70 square miles were under mandatory orders to get out.
Jaenette Coyne was one of those ordered to leave as quickly as possible.
After calling 911 to report smoke behind her home, Coyne estimated she had five minutes to leave home. There was no time to grab wedding albums, fingerprint artwork by her 20-month-old daughter, quilts her grandmother made or the family's three cats.
"We left with nothing," she said.
She and her husband later watched on television as flames engulfed their house.
"I don't know how to tell you in words what it felt like," she said. "It's the worst thing I've ever felt in my whole life."
Part of neighboring Elbert County, including two camps with about 1,250 children and adults, was also evacuated.
No injuries or deaths have been reported, but Maketa said officials are trying to confirm the whereabouts of one person reported missing.
The fire was among several that have been burning along Colorado's Front Range. Wildfires were also burning in New Mexico, Oregon and California, where a smokejumper was killed fighting one of dozens of lightning-sparked blazes.
The U.S. Forest Service on Wednesday mobilized a pair of Defense Department cargo planes to help ? a step taken only when all of the Forest Service's 12 contracted tankers are in use. At least one was fighting the Black Forest fire.
About 60 miles southwest of the Black Forest, a 4.5-square-mile wildfire that evacuated Royal Gorge Bridge & Park has destroyed 20 structures, including some in the park.
The Royal Gorge suspension bridge spanning a canyon across the Arkansas River has fire damage to 32 of its 1,292 wooden planks, city officials said. An aerial tram car and tram buildings on either side of the gorge were destroyed, and the tram cable fell into the gorge. An incline railway descending 1,500 feet to the canyon floor was damaged.
Another fire sparked by lightning Monday in Rocky Mountain National Park has grown to an estimated 600 acres in area with trees killed by pine beetles.
Gov. John Hickenlooper has declared disaster emergencies for the Black Forest and Royal Gorge fires and a 60-acre fire in rural Huerfano County, authorizing a combined $10.15 million to help pay for firefighting and other costs.
At a Wal-Mart and Home Depot parking lot, evacuees Greg and Sharon Rambo set up camp. They had been living in a modular home in Black Forest as they waited to close on a larger house nearby. They believe both have burned.
"It leaves you feeling numb, loss of appetite, disoriented," Greg Rambo said.
The couple previously lived in Southern California and were evacuated during a 2004 blaze that hopscotched over their property without damaging it. Since then, they have carried a briefcase filled with medications and important documents, and kept their trailer far from their house so they'd have a place to sleep in the event their home burns down.
Their daughter, who lives nearby, called them Tuesday and urged them to flee. They do not know if her house also burned.
Meanwhile, Coyne said, her young daughter has been asking when her family can go home and "see their kitties." She said the family has a place to stay but could use guidance on what to do next.
"What do you do when you've lost everything," she said.
___
Associated Press writers Steven K. Paulson, Ivan Moreno and Catherine Tsai in Denver contributed to this report.
Source: http://news.yahoo.com/1-000-colo-springs-homes-evacuating-due-fire-202416598.html
Tony Sly Lauren Perdue tagged Heptathlon London 2012 shot put London 2012 Track And Field Jordyn Wieber
The Organ Procurement and Transplantation Network voted to keep the so-called Under 12 Rule, but it created a mechanism that would allow doctors to request exceptions for their pediatric patients. A national lung review board would then approve these children for transplant consideration as adults case by case.
The transplant network convened an emergency meeting of its executive committee to evaluate the Under 12 Rule, a little-known organ transplant policy that a Pennsylvania couple brought to national attention after arguing that it had been pushing their dying 10-year-old to the bottom of the adult lung transplant waiting list.
Lawyers for Sarah Murnaghan, who is dying of cystic fibrosis, convinced federal Judge Michael Baylson on June 5 that the Under 12 Rule was discriminatory, prompting a temporary restraining order against Health and Human Services Secretary Kathleen Sebelius to prevent her from enforcing it for Sarah.
Read about the Murnaghans' battle to save Sarah.
Baylson's ruling forced OPTN to create a second database entry for Sarah with a fake birthday to trick the organ transplant system into thinking she was 12. The following day, another child in Sarah's hospital, Javier Acosta, 11, won the same reprieve.
Courtesy Pepper Hamilton LLP | Courtesy Murnaghan Family
Girl, 10, Denied Lung Transplant Due to Age Policy Watch Video Lung Transplant Patient Gets Donor From Same Hospital Watch Video California Man Undergoes 'Breathing Lung' Transplant Watch VideoRead about how Javier's brother died waiting for a lung transplant when he was 11.
But the OPTN decision doesn't mean Sarah's and Javier's cases need to go before a national lung review board immediately to keep their transplant database entries in the system. Since the courts forced OPTN to create these entries, a hearing scheduled for June 14 will determine whether they can stay where they are on the list or whether their cases need to be evaluated by the review board.
Sarah's mother, Janet Murnaghan, took to Facebook following OPTN's decision.
"We consider this a tremendous win for Sarah and all kids waiting for lungs!!!" she wrote. "I hope Sarah's story moves people to become organ donors, because more than any ruling it is the heroes who donate their organs that save lives."
Part of the OPTN meeting, which convened via teleconference, was dedicated to the ethics of judicial intervention in organ allocation and the fear that transplant candidates would sue to increase their likelihoods of getting the organs they need.
"Politicians and judges who intervene in a complex allocation algorithm may be well-intentioned but fail to consider all the moral variables that must be balanced at the macro level rather than through an individual candidate's experience," the OPTN ethics committee concluded. "The message that lawsuits are a mechanism for more favorable organ allocation runs the risk of disrupting a stable system based on public trust. For patients waiting for transplantation, the resulting lack of predictability may have unintended and lethal consequences."
Several medical, legal and health experts had condemned Baylson's ruling before the OPTN decision, arguing that existing lung allocation practices ?- including the Under 12 Rule -- are based on medical evidence, and that allowing Sarah and Javier to be given special priority without OPTN approval was unfair to other candidates on the list.
"It is unlikely that the courts are the best place to make these decisions," said R. Alta Charo, a law and bioethics professor at the University of Wisconsin-Madison. "The reasons for giving priority to one category of patients over another are usually due to a complicated combination of factors."
Source: http://abcnews.go.com/Health/girl-prompts-small-change-organ-transplant-policy/story?id=19373685
tonga pid corned beef hash the walking dead season 2 finale born free walking dead finale nascar bristol
