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Tuesday, January 10, 2012
Around the Web?
Another week begins! Start your Monday with today’s links: Blue Ivy Carter: What’s in a name? ? PEOPLE How to grocery shop for family on a budget ? BreezyMama.com MotherKnows app provides 24-hour access to children’s medical records ? Tecca.com Katherine Heigl: Working makes me ‘a better mother’ ? iVillage.com Healthy diet can serve as [...]
shelllivewireuk: We aim to get 1,000 Facebook Fans by end of Jan. If u haven't already could u pls 'Like' our page? http://t.co/WdY2gQAa
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We aim to get 1,000 Facebook Fans by end of Jan. If u haven't already could u pls 'Like' our page? facebook.com/ShellLiveWIREUK 
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Monday, January 9, 2012
SolarKindle Cover Is Walking On Sunshine (Whoaaa!)
I've done my fair share of Kindle cover research, and to tell you the truth I wish this new cover from SolarFocus was around when I did. It's the world's first solar cover for the Kindle, with a solar panel built right in. The SolarKindle promises "up to three months of unplugged Kindle use under normal sunlight environment." In my experience that means near a window, which should be easy enough.Source: http://feedproxy.google.com/~r/Techcrunch/~3/azEhFk9Rph8/
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Knicks Vs. Wizards Final Score: Carmelo Anthony Leads New York Past Still Winless Washington
The Wizards losing streak continued on Friday night with a heartbreaking 99-96 loss to the New York Knicks at Verizon Center.
Carmelo Anthony hit a deep three pointer to give the Knicks a two point lead with 15 seconds remaining. At first glance, one had to wonder how a red hot Anthony had so much room as he was relatively wide open outside the arc. But replay showed Anthony catching Trevor Booker in the face and eye with his off hand. Booker reacted and grabbed his eye with that slight hesitation giving Anthony all the room he needed to drain the game winning three.
On the ensuing possession, John Wall would miss a go-ahead three pointer of his own. It was missed so badly, however, that the long rebound bounced right into the hand of Chris Singleton. Singleton rushed the put back which came up well short. The Knicks controlled the rebound but missed one of two free throw attempts to give the Wizards a chance to get off a game-tying three pointer. Nick Young's heave would draw the back of the iron, however, and Washington would drop their seventh in a row to open the 2011-12 season.
Anthony was on fire in the fourth quarter, as the Knicks continually fed 'Melo both in the post and on the wing. He finished with a game-high 37 points. Nick Young led the Wizards with 24 points, while Wall added 22 points. Wall really pushed the pace in the fourth, hitting a couple miraculous up-and-under layups in traffic. - including one which gave the Wiz the lead before Anthony's three pointer. He finished 10 of 22 from the floor with nine assists and five turnovers.
Washington will now try for the first win on Sunday when they host the Minnesota Timberwolves.
For more on the Wizards, please visit Bullets Forever, SB Nation's Wizards blog. For the perspective from the other side, please visit SB Nation New York and Posting and Toasting, SB Nation's Knicks blog.
Source: http://dc.sbnation.com/washington-wizards/2012/1/6/2688608/knicks-vs-wizards-final-score-nba-recap
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Saturday, January 7, 2012
Google adds more IBM patents to tech arsenal
Google on Wednesday confirmed that it has added more IBM patents to its technology arsenal as smartphone rivals increasingly battle in courts over innovations. Google bought 188 patents and 29 patent applications related to mobile phones from IBM but did not disclose how much it paid.?
Source: http://c.moreover.com/click/here.pl?r5715049261&f=378
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Galaxy Nexus coming to Sprint's LTE network? This ad says so.
We're looking at a familiar 4.65-inch HD Super AMOLED display, Android 4.0, a 1080p movie mode, front and rear cameras, and a 1.5GHz dual-core processor. For those keeping count, that's 300MHz more powerful than the 1.2GHz chip in the HSPA+ and VZW models. If you're going to launch an LTE network, might as well snag a phone like this, right? Maybe. What's strange is that the first LTE markets for Sprint won't light up until the middle of the year, at which point the device beaming above will likely be old news. Beyond that, there's the question of Sprint's unlimited stance -- the operator's been holding firm to date, but it'll surely become harder to justify a "truly unlimited" option when its smartphone base starts flocking to handsets like these.
[Thanks, James]
Continue reading Galaxy Nexus coming to Sprint's LTE network? This ad says so.
Galaxy Nexus coming to Sprint's LTE network? This ad says so. originally appeared on Engadget on Thu, 05 Jan 2012 17:07:00 EDT. Please see our terms for use of feeds.
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Thursday, January 5, 2012
Benefits of statin therapy may extend beyond lowering lipids
ScienceDaily (Jan. 4, 2012) ? People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.
For years, scientists have studied the cause of this abnormal clotting. Now, a study led by researchers from the University of North Carolina at Chapel Hill School of Medicine has identified a molecular pathway that leads to this abnormal blood clotting. The researchers then turned off the pathway by using a popular class of cholesterol-lowering drugs, statins.
The research was performed using humans, monkeys and mice with highly elevated blood lipid levels. It indicated that elevated levels of oxidized low density lipoprotein (LDL) induces a molecule called "tissue factor" that triggers clotting. The study appears online in the January 3, 2012 issue of the Journal of Clinical Investigation.
"Statins have been shown to have antithrombotic activity in several previous studies. However, I believe our study is the first to elucidate how statins reduce the activation of the blood clotting process independently of their lipid lowering activity, said senior study author Nigel Mackman, PhD, FAHA. Mackman is the John C. Parker Distinguished Professor of Hematology in the Department of Medicine and Director of the UNC McAllister Heart Institute.
Additionally, Mackman noted that statins "only target the 'bad and inducible tissue factor', not the good one used in normal clotting, and therefore should not be associated with the increased bleeding risk that is a typical side effect of anticoagulant drugs currently on the market."
Mackman has spent the last twenty-five years studying tissue factor, the number one initiator of clotting in the body. Tissue factor normally resides outside the blood vessels, only coming into contact with blood after an injury, such as cutting your finger. However, it is expressed at high levels under certain abnormal conditions, such as inside atherosclerotic plaques, and gets turned on in a special subset of blood cells called monocytes. Mackman wondered if this was the cause for the abnormal clotting seen in patients with high cholesterol.
To test his hypothesis, Mackman and his colleagues analyzed humans, monkeys and mice with high cholesterol. They found that all three groups have elevated levels of tissue factor in the circulation.
Then the researchers treated the mice and monkeys with simvastatin, a drug widely used to treat high blood cholesterol levels. They showed that simvastatin reduced levels of oxidized low density lipoprotein and circulating tissue factor which normalized coagulation without altering plasma cholesterol levels. These results suggest that oxidized low density lipoproteins induce tissue factor expression on monocytes and this contributes to formation of an occlusive thrombus after plaque rupture.
"Though statin therapy is primarily prescribed to lower cholesterol, some added benefits are its anti-inflammatory and antithrombotic activities," said Mackman. "In terms of drug development, I think we should be trying to better understand the antithrombotic activities of statins so we can develop safer antithrombotic drugs that target the expression of inducible tissue factor."
The research was funded largely by the National Heart, Lung and Blood Institute, a component of the National Institutes of Health. The majority of this work was performed by A. Phillip Owens III, PhD. Other study co-authors from Dr. Mackman's lab at UNC were Silvio Antoniak, PhD; Julie C. Williams; and Jianguo Wang, PhD.
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The above story is reprinted from materials provided by University of North Carolina School of Medicine.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- A. Phillip Owens, Freda H. Passam, Silvio Antoniak, Stephanie M. Marshall, Allison L. McDaniel, Lawrence Rudel, Julie C. Williams, Brian K. Hubbard, Julie-Ann Dutton, Jianguo Wang, Peter S. Tobias, Linda K. Curtiss, Alan Daugherty, Daniel Kirchhofer, James P. Luyendyk, Patrick M. Moriarty, Shanmugam Nagarajan, Barbara C. Furie, Bruce Furie, Douglas G. Johns, Ryan E. Temel, Nigel Mackman. Monocyte tissue factor?dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. Journal of Clinical Investigation, 2012; DOI: 10.1172/JCI58969
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://www.sciencedaily.com/releases/2012/01/120104153743.htm
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